First Avenue

First Avenue can refer to:

• First Avenue (Manhattan), a major thoroughfare in New York City
• First Avenue Records, a former record label acquired by Arista Records
• First Avenue South Bridge, a bridge in Seattle
• First Avenue (PAT station), a station on the Port Authority of Allegheny County's light rail network
• First Avenue Public School, an elementary school in Ottawa, Ontario, Canada
• First Avenue (BMT Canarsie Line), a subway station
• First Avenue (nightclub), a music venue in downtown Minneapolis, Minnesota